Cryolipolysis: Is it Science or Science Fiction? Experts Reveal Findings

Photographed by Steven Klein, Vogue, December 2008
Non-invasive fat reduction treatments using controlled cooling, also known as cryolipolysis, to literally freeze fat may seem too good to be true. But scientific research reveals the revolutionary technology behind CoolSculpting, America’s most popular non-invasive fat reduction procedure, effectively and safely reduces belly fat, thigh fat, back fat, muffin tops, bra bulge, double chins and more.


So is CoolSculpting using Cryolipolysis technology an effective treatment for dealing with stubborn fat deposits that won’t respond to diet and exercise? We surveyed the existing data on Cryolipolysis body contouring technology, leaving it to the experts to substantiate the raving coolsculpting  reviews* and amazing coolsculpting before and after pics*, with their scientific findings.


What is Cryolipolysis?

Dr. Avram and Harry, in their article “Cryolipolysis for Subcutaneous Fat Layer Reduction” for the scholarly journal Lasers in Surgery and Medicine explain that:


CoolSculpting which uses “Cryolipolysis is a unique non-invasive method for the selective reduction of fat cells with controlled, localized cooling.”


Is there scientific evidence supporting the safety and efficacy of cryolipolysis?

Yes. And there is a lot of it. The ample amount of clinical research investigating cryolipolysis as a mechanism for fat reduction is noted in the scholarly article “Cryolipolysis For Noninvasive Body Contouring: Clinical Efficacy And Patient Satisfaction” published in the journal of Clinical, Cosmetic, Investigational Dermatology. Nils Krueger and his fellow researchers who conducted the study notes:


CoolSculpting which uses Cryolipolysis, has “not only been commercially available for the longest time, but has also been best researched” among the “number of modalities…available for the noninvasive reduction of [fat.]”


The mechanism of Cryolipolysis: How does CoolSculpting work?

Krueger explains “The principle behind cryolipolysis exploits the premise that adipocytes [fat cells] are more susceptible to cooling than other skin cells. The precise application of cold temperatures triggers apoptosis [cell death] of the adipocytes, [fat cells] which invokes an inflammatory response and leads to slow digestion by surrounding macrophages [the white blood cells that rid the body of waste.]”¹*


In simpler terms when Cryolipolysis is delivered during the CoolSculpting procedure, controlled cooling is applied to an area of the body. The cooling safely passes through the skin and surrounding tissue and penetrates the fatty tissue beneath. Some of the fat is then frozen, effectively destroying those fat cells, which are gradually picked up by the body’s natural healing process and secreted out of the body as waste.*


Allure magazine explained how controlled cooling can freeze and destroy fat cells, without harming surrounding tissue in their interview of Dr. Dieter Manstein of Harvard Medical school,  the scientist credited for discovering the Cryolipolysis, the revolutionary fat reduction procedure that Allure magazine dubbed “non-invasive liposuction.”


Dr. Dieter Manstein, explains “Fat freezes at a higher temperature than water. Think of butter and water in the refrigerator – one is solid, the other remains liquid.” Allure magazine explains the significance of this observation “In other words, [Dr. Manstein] realized he could freeze an amount of  fat, which would destroy fat cells but do no harm to the overlying tissue.” *

Read the full article from Allure here > >


Does CoolSculpting Work?

The consensus of the scientific community is empirically yes!


Nils Krueger and his fellow researchers conclude: “cryolipolysis is considered to be both safe and efficient with a high patient satisfaction rate.”*


Authors of the article “Safety, Tolerance, And Patient Satisfaction With Noninvasive Cryolipolysis.” found in the journal of Dermatological surgery confirm:


“cryolipolysis is a safe, well-tolerated, and effective treatment method for reduction of subcutaneous fat.”


In the article published in the Journal of Lasers in Surgery and Medicine titled “Safety And Efficacy Of Cryolipolysis For Non-Invasive Reduction Of Submental Fat researchers evaluated the CoolMini for reducing fat that forms a double chin and reported:


“The results of this clinical evaluation of 60 patients treated in a pivotal IDE study demonstrate that submental fat can be reduced safely and effectively with a small volume cryolipolysis applicator.*”

Learn more about reducing double chin fat with the CoolMini from SKINNEY Medspa >>


Researches Avram and Harry summarize the bulk of research conducted on cryolipolysis for non-invasive fat reduction concluding:


“Although the mechanism of action for cryolipolysis is not yet completely understood, the efficacy and safety of this non-invasive procedure for fat layer reduction has been demonstrated in the studies available to data.”¹


How effective is Cryolipolysis?

The researchers of “Cryolipolysis For Noninvasive Body Contouring reported


“In clinical studies, cryolipolysis was shown to reduce subcutaneous fat at the treatment site by up to 25% after one treatment.” *¹


The authors of “Safety, Tolerance, And Patient Satisfaction With Noninvasive Cryolipolysis.” report:


“Caliper measurements demonstrated 23% reduction in fat layer thickness at 3 months. Abdomen, back, and flank treatment sites were most effective, with 86% of subjects showing improvement per investigator assessment.”*


Evaluating the efficiency of CoolSculpting’s newest application head, the CoolMini, in the article “Safety And Efficacy Of Cryolipolysis For Non-Invasive Reduction Of Submental Fat.” published  in the Journal of Lasers in Surgery and Medicine measuring the physically noticeable improvement when Cryolipolysis is used to reduce fat from the neck and chin area, researchers report:


“Independent photo review from 3 blinded physicians found 91% correct identification of baseline clinical photographs. Ultrasound data indicated mean fat layer reduction of 2.0 mm.”


“Learn more about CoolSculpting from SKINNEY Medspa and receive 20% your first fat reduction treatment”

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